Rejeunesse Deep

Rejeunesse is a non-animal-based, cross-linked hyaluronic acid (HA) dermal filler developed by NewMedic Co., Ltd., a South Korean biopharmaceutical company. It corrects wrinkles and folds, restores facial volume, and rehydrates the skin.

NewMedic builds Rejeunesse using proprietary UPHEC purification technology. As a result, the finished gel keeps endotoxin levels below 1.2 EU/mL and shows no detectable BDDE residue. This combination supports high purity and low risk of immunogenic reaction after treatment.

Korea Filler Experts sources Rejeunesse directly from Korea and ships it worldwide.

Key Benefits

• Corrects wrinkles and folds — the Rejeunesse range spans superficial lines to deep facial folds
• Restores facial volume — rebuilds contour and lift in the cheeks, chin, and lips
• Delivers immediate, stable results — patients see volume effects right after injection, with minimized swelling
• Reduces injection discomfort — 0.3% lidocaine is built into the formula to minimize pain during treatment
• Resists migration — high concentration cross-linking (HCCL) technology keeps the gel close to the injection site
• Offers long-lasting results — most patients see effects for 12 to 18 months, depending on the product and treatment area

What’s Inside

How Rejeunesse Works

Hyaluronic acid occurs naturally in the skin, where it maintains hydration, firmness, and elasticity. However, natural HA breaks down quickly in the body. So NewMedic cross-links the HA in Rejeunesse using BDDE as the linking agent, which slows breakdown and extends the filler’s effects.

Once injected, the gel fills wrinkles and depressions, restoring lost facial volume. Because the HCCL process keeps the gel’s viscoelasticity carefully tuned, it stays close to the injection site rather than migrating. Over time, the body gradually absorbs the gel through natural processes.

Who Is Rejeunesse Suited For?

Practitioners use the Rejeunesse range for patients who have:

• Superficial wrinkles, such as crow’s feet and perioral lines (Rejeunesse Fine)
• Deep folds and wrinkles, including nasolabial folds and periorbital lines (Rejeunesse Deep)
• A need for facial contouring, cheek, or chin augmentation (Rejeunesse Shape)
• Dehydrated, dull skin in need of light rejuvenation (Rejeunesse Sparkle)
• Lip volume loss or a desire for fuller lip definition

Recommended Injection Technique

• Inject into the mid-to-deep dermis or subcutaneous layer, depending on the product and desired correction depth.
• Use the pre-attached 27G needle for controlled, precise placement.
• For contouring products, injection into the subcutaneous or supraperiosteal layer is common.
• Space touch-up sessions according to the specific product’s duration profile.

Note: licensed and trained medical aesthetics professionals should administer this product only.

Treatment Areas

Crow’s feet · Perioral lines · Nasolabial folds · Periorbital wrinkles · Cheeks · Chin and jawline · Lips · General skin rehydration

Recommended Treatment Course

• Duration: results typically last 12–18 months for Deep and Shape formulas, or 6–8 months for lighter formulas like Sparkle
• Maintenance: follow-up sessions are scheduled once initial results begin to soften
• Onset: volume and contour improvements are visible immediately after injection

Storage & Handling

• Store at 2°C–25°C (room temperature is acceptable)
• Do not freeze or heat the product
• Keep the syringe in its original sterile packaging until use
• Shelf life: 24 months from the manufacturing date; single use only

Frequently Asked Questions

What is Rejeunesse?
Rejeunesse is a cross-linked hyaluronic acid dermal filler made by NewMedic Co. It corrects wrinkles, restores facial volume, and hydrates the skin.

What’s the difference between Fine, Deep, Shape, and Sparkle?
Fine targets superficial wrinkles. Deep treats medium-to-deep folds. Shape is built for facial contouring and augmentation. Sparkle is a lighter formula for general skin hydration and rejuvenation.

How long do results last?
Most Rejeunesse products last 12 to 18 months. Lighter formulas like Sparkle typically last 6 to 8 months.

Is Rejeunesse safe?
Yes — Rejeunesse uses non-animal-derived HA, and its UPHEC purification process removes detectable BDDE residue while keeping endotoxin levels low. A trained professional should always administer it.

Does Rejeunesse contain lidocaine?
Yes, the standard formula includes 0.3% lidocaine hydrochloride to reduce discomfort during and after injection.