Liporase Inj. — Hyaluronidase Filler Dissolver

Liporase Inj. is a hyaluronidase enzyme solution from Daehan New Pharm in South Korea. Its primary role is dissolving hyaluronic acid (HA) dermal fillers, whether a practitioner overfilled the area, placed the filler unevenly, or injected it incorrectly. Because of this, many clinics treat it as an essential item to keep on hand for any HA filler treatment.

Beyond routine correction, Liporase also plays a critical safety role. If a practitioner accidentally injects filler into a blood vessel, prompt hyaluronidase administration can help resolve the resulting vascular complication. For this reason alone, many practitioners treat it as a must-have alongside any HA filler stock.

Each pack contains 10 vials of hyaluronidase powder, with 1,500 IU per vial.

Korea Filler Experts offers Liporase Inj. and ships it worldwide.

• Dissolves HA-based dermal fillers quickly and effectively
• Supports emergency correction of vascular complications from filler injection
• Enhances the effect of fat-dissolving injection procedures
• Delivers visible results within 24 to 48 hours
• Comes in a precisely dosed, easy-to-reconstitute powder form
• Carries MFDS approval for safety and quality

Hyaluronidase is an enzyme that breaks the glycosidic bonds holding hyaluronic acid molecules together. Once these bonds break, the HA separates into smaller monosaccharide units. As a result, the body absorbs and clears these fragments naturally, effectively reversing the filler’s volumizing effect.

This same mechanism explains its secondary use alongside fat-dissolving injections. Because hyaluronidase weakens the surrounding tissue membrane, it helps other injected compounds absorb more efficiently. Consequently, this can enhance the results of lipolysis treatments.

Practitioners keep Liporase Inj. on hand for:

• Correcting overfilled, uneven, or poorly placed HA filler results
• Emergency response to vascular occlusion from filler injection
• Enhancing fat-dissolving injection procedures
• General practice safety stock for any clinic offering HA fillers

To prepare Liporase for use, practitioners typically mix 3cc of saline into one vial of hyaluronidase powder. This dilution dissolves approximately 3cc of hyaluronic acid. Because comfort matters during the procedure, many practitioners also inject Liporase alongside lidocaine to help manage discomfort.

• Inject the reconstituted solution into the area requiring correction
• HA filler typically begins dissolving immediately and clears within a few hours
• Massage the treated area for about 15 minutes daily for one week
• Apply a warm compress to the area after each massage session

Hyaluronidase can trigger allergic reactions in some patients, including those with sensitivities related to bee sting allergies, since bee venom also contains hyaluronidase. Because of this, practitioners should strongly consider a patch test before full treatment. Antibiotics cannot treat allergic reactions to hyaluronidase, so practitioners should prepare to address hypersensitivity reactions appropriately if they occur.

• Store unopened vials in a cool, dry place, ideally refrigerated between 2°C and 8°C
• Use the reconstituted solution promptly after mixing
• For professional use only, by qualified and trained practitioners

What is Liporase Inj.?
Liporase Inj. is a hyaluronidase enzyme solution from Daehan New Pharm. Practitioners use it to dissolve HA-based dermal fillers and address related vascular complications.

How quickly does Liporase work?
Visible effects typically appear within 24 to 48 hours, though the exact timeline depends on the filler’s location and formulation.

Why is Liporase considered essential for clinics using HA fillers?
Because it can rapidly reverse HA filler placement, including in emergencies involving accidental vascular injection, many practitioners keep it on hand as a safety precaution.

Should patients be tested before using Liporase?
Yes. Practitioners should recommend a patch test before full treatment, since hyaluronidase can occasionally trigger allergic reactions.